Naproxen vs. opioid combo after dental surgical procedure: Outcomes shock researchers
New analysis on the efficacy of nonprescription naproxen sodium (NapS) for relieving ache after dental procedures affirms a rising physique of proof that NapS and different nonsteroidal anti-inflammatory medication (NSAIDs) mitigate using opioid mixtures as a primary strategy for relieving minor ache after dental procedures.
In December, a single dose examine by Bayer Shopper Well being Division discovered that in treating moderate-to-severe postsurgical dental ache, a single dose of nonprescription naproxen sodium 440 mg (NapS) was at the very least as efficient via hour 4 post-surgery and higher tolerated than a single dose of an opioid mixture of hydrocodone plus acetaminophen.
New analysis by JBR Medical Analysis in Salt Lake Metropolis performed on sufferers experiencing average to extreme ache after knowledge tooth extraction additionally in contrast the efficacy of a single, nonprescription dose of naproxen with that of hydrocodone plus acetaminophen, the outcomes of which affirmed “a big physique of proof…that reveals nonsteroidal anti-inflammatory medication, like naproxen, are extremely efficient for acute postoperative ache, equivalent to post-dental surgical procedure ache.”
What shocked the researchers within the JBR examine, revealed in Ache Drugs Information, was that “the naproxen group outperformed the group that acquired opioids on all major and secondary finish factors,” with sufferers who took naproxen reporting much less intense ache and longer-lasting reduction than the group on opioids.
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Naproxen simpler than hydrocodone-acetaminophen after dental surgical procedure